MolNFT v1 · #299325 · protein
AlphaFold monomer V2.0 prediction for prkca-binding protein (Q9EP80)
Q9EP80: “AlphaFold monomer V2.0 prediction for prkca-binding protein (Q9EP80)”. 6 pockets (best druggability 0.38). MolNFT v1 #299325 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9EP80
- Type
- protein
- Length
- 416 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Prkca-binding protein
- UniProt
- Q9EP80
- Pockets
- 6 · best druggability 0.38
Structure
1 distinct chain · 57% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prkca-binding protein | protein | 416 | 57% helix, 9% strand | Q9EP80 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.38 | 0.78 | 18 | empty |
| 2 | 61 | 0.36 | 0.78 | 12 | empty |
| 3 | 92 | 0.36 | 0.75 | 20 | empty |
| 4 | 51 | 0.34 | 0.78 | 12 | empty |
| 5 | 70 | 0.33 | 0.75 | 15 | empty |
Compared structures
- 2LUI · Structure of the PICK PDZ domain in complex with the DAT C-terminal · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 2LUI · Structure of the pick PDZ domain in complex with the dat C-terminal · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 2PKU · Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2PKU · Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GLUR2 · an experimental structure of the same protein · chain A against A, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9EP80
- Elsewhere: UniProt Q9EP80 · AlphaFold DB Q9EP80
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