MolNFT v1 · #299235 · protein
AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase alpha (O02811)
O02811: “AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase alpha (O02811)”. 20 pockets (best druggability 0.81). MolNFT v1 #299235 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O02811
- Type
- protein
- Length
- 2,102 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7782F4817b37743d738e9aF842bf74bd50f2015E
- Molecule
- Phosphatidylinositol 4-kinase alpha
- UniProt
- O02811
- Pockets
- 20 · best druggability 0.81
Structure
1 distinct chain · 62% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol 4-kinase alpha | protein | 2102 | 62% helix, 4% strand | O02811 |
Pockets
20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 989 | 0.81 | 0.82 | 94 | empty |
| 2 | 610 | 0.79 | 0.85 | 88 | empty |
| 3 | 484 | 0.79 | 0.86 | 58 | empty |
| 4 | 400 | 0.77 | 0.86 | 55 | empty |
| 5 | 750 | 0.71 | 0.78 | 49 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O02811
- Elsewhere: UniProt O02811 · AlphaFold DB O02811
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