MolNFT v1 · #299215 · protein
AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory subunit 5 (Q5SW28)
Q5SW28: “AlphaFold monomer V2.0 prediction for phosphoinositide 3-kinase regulatory subunit 5 (Q5SW28)”. 10 pockets (best druggability 0.78). MolNFT v1 #299215 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5SW28
- Type
- protein
- Length
- 871 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6c05b483540F55289d602403d0273aF68B0db5F9
- Molecule
- Phosphoinositide 3-kinase regulatory subunit 5
- UniProt
- Q5SW28
- Pockets
- 10 · best druggability 0.78
Structure
1 distinct chain · 31% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoinositide 3-kinase regulatory subunit 5 | protein | 871 | 31% helix, 16% strand | Q5SW28 |
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 981 | 0.78 | 0.80 | 77 | empty |
| 2 | 909 | 0.75 | 0.79 | 71 | empty |
| 3 | 540 | 0.65 | 0.76 | 45 | empty |
| 4 | 82 | 0.53 | 0.85 | 21 | empty |
| 5 | 253 | 0.52 | 0.75 | 31 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SW28
- Elsewhere: UniProt Q5SW28 · AlphaFold DB Q5SW28
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