MolNFT v1 · #298536 · protein

AlphaFold monomer V2.0 prediction for alkaline phosphatase synthesis sensor protein phor (P23545)

P23545: “AlphaFold monomer V2.0 prediction for alkaline phosphatase synthesis sensor protein phor (P23545)”. 4 pockets (best druggability 0.70). MolNFT v1 #298536 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P23545
Type: protein
Length: 579 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8edD144f4ac42c0531a333DF70DD4843E3D334A9
Molecule: Alkaline phosphatase synthesis sensor protein phor
UniProt: P23545
Pockets: 4 · best druggability 0.70

Structure

1 distinct chain · 52% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alkaline phosphatase synthesis sensor protein phor	protein	579	52% helix, 22% strand	P23545

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	330	0.70	0.84	44	empty
2	170	0.46	0.76	24	empty
3	103	0.39	0.76	19	empty
4	52	0.27	0.74	10	empty

Compared structures

3CWF · Crystal structure of PAS domain of two-component sensor histidine kinase · an experimental structure of the same protein · chain A against B, TM-score 0.18
3CWF · Crystal structure of pas domain of two-component sensor histidine kinase · an experimental structure of the same protein · chain A against B, TM-score 0.18

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23545
Elsewhere: UniProt P23545 · AlphaFold DB P23545

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