MolNFT v1 · #297808 · protein

AlphaFold monomer V2.0 prediction for histone lysine demethylase PHF8 (Q80TJ7)

Q80TJ7: “AlphaFold monomer V2.0 prediction for histone lysine demethylase PHF8 (Q80TJ7)”. 5 pockets (best druggability 0.84). MolNFT v1 #297808 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q80TJ7
Type: protein
Length: 1,023 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
Molecule: Histone lysine demethylase PHF8
UniProt: Q80TJ7
Pockets: 5 · best druggability 0.84

Structure

1 distinct chain · 20% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histone lysine demethylase PHF8	protein	1023	20% helix, 9% strand	Q80TJ7

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	982	0.84	0.85	73	empty
2	189	0.50	0.76	17	empty
3	117	0.38	0.74	20	empty
4	93	0.36	0.75	13	empty
5	58	0.31	0.76	9	empty

Compared structures

1WEP · Solution structure of PHD domain in PHF8 · an experimental structure of the same protein · chain A against A, TM-score 0.07
1WEP · Solution structure of phd domain in PHF8 · an experimental structure of the same protein · chain A against A, TM-score 0.07

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80TJ7
Elsewhere: UniProt Q80TJ7 · AlphaFold DB Q80TJ7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.