MolNFT v1 · #297752 · protein
AlphaFold monomer V2.0 prediction for phosphate-regulating neutral endopeptidase phex (P70669)
P70669: “AlphaFold monomer V2.0 prediction for phosphate-regulating neutral endopeptidase phex (P70669)”. 7 pockets (best druggability 0.72). MolNFT v1 #297752 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P70669
- Type
- protein
- Length
- 749 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
- Molecule
- Phosphate-regulating neutral endopeptidase phex
- UniProt
- P70669
- Pockets
- 7 · best druggability 0.72
Structure
1 distinct chain · 57% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphate-regulating neutral endopeptidase phex | protein | 749 | 57% helix, 7% strand | P70669 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 724 | 0.72 | 0.78 | 64 | empty |
| 2 | 553 | 0.68 | 0.78 | 73 | empty |
| 3 | 86 | 0.46 | 0.81 | 20 | empty |
| 4 | 84 | 0.35 | 0.75 | 15 | empty |
| 5 | 65 | 0.33 | 0.76 | 12 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P70669
- Elsewhere: UniProt P70669 · AlphaFold DB P70669
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