MolNFT v1 · #297368 · protein
AlphaFold monomer V2.0 prediction for geranylgeranyl transferase type-1 subunit beta (P53610)
P53610: “AlphaFold monomer V2.0 prediction for geranylgeranyl transferase type-1 subunit beta (P53610)”. 4 pockets (best druggability 0.65). MolNFT v1 #297368 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P53610
- Type
- protein
- Length
- 377 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Geranylgeranyl transferase type-1 subunit beta
- UniProt
- P53610
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 52% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Geranylgeranyl transferase type-1 subunit beta | protein | 377 | 52% helix, 5% strand | P53610 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 360 | 0.65 | 0.79 | 37 | empty |
| 2 | 66 | 0.44 | 0.82 | 21 | empty |
| 3 | 90 | 0.39 | 0.77 | 16 | empty |
| 4 | 56 | 0.24 | 0.72 | 17 | empty |
Compared structures
- 1TNY · Rat protein geranylgeranyltransferase type-I complexed with a ggpp analog and a… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1TNY · Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4Q · Protein Geranylgeranyltransferase type-I Complexed with a GGPP Analog and a KKKSKTKCVIL… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4Q · Protein geranylgeranyltransferase type-I complexed with a ggpp analog and a kkksktkcvil… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1TNB · Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1TNB · Rat protein geranylgeranyltransferase type-I complexed with a ggpp analog and a substrate… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4R · Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4R · Protein geranylgeranyltransferase type-I complexed with a geranylgeranylated kkksktkcvil… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1TNZ · Rat protein geranylgeranyltransferase type-I complexed with a ggpp analog and a rrcvll… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1TNZ · Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a RRCVLL… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4S · Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated… · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 1N4S · Protein geranylgeranyltransferase type-I complexed with ggpp and a geranylgeranylated… · an experimental structure of the same protein · chain A against B, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53610
- Elsewhere: UniProt P53610 · AlphaFold DB P53610
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