MolNFT v1 · #297268 · protein

AlphaFold monomer V2.0 prediction for biglycan (P21809)

P21809: “AlphaFold monomer V2.0 prediction for biglycan (P21809)”. 5 pockets (best druggability 0.51). MolNFT v1 #297268 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P21809
Type: protein
Length: 369 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x56DC0c916DDD307629592C2D2Cfd6e8dc1fA4CB7
Molecule: Biglycan
UniProt: P21809
Pockets: 5 · best druggability 0.51

Structure

1 distinct chain · 8% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Biglycan	protein	369	8% helix, 15% strand	P21809

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.51	0.79	25	empty
2	99	0.39	0.75	11	empty
3	85	0.36	0.75	11	empty
4	72	0.31	0.74	16	empty
5	55	0.31	0.76	12	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2FT3 · Crystal structure of the biglycan dimer core protein · an experimental structure of the same protein · chain A against F, TM-score 0.82
2FT3 · Crystal structure of the biglycan dimer core protein · an experimental structure of the same protein · chain A against F, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21809
Elsewhere: UniProt P21809 · AlphaFold DB P21809

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