MolNFT v1 · #296110 · protein
AlphaFold monomer V2.0 prediction for aggrecan core protein (P13608)
P13608: “AlphaFold monomer V2.0 prediction for aggrecan core protein (P13608)”. 17 pockets (best druggability 0.75). MolNFT v1 #296110 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P13608
- Type
- protein
- Length
- 2,364 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x32Dd5B71E48E579114B6a52f6D2542974C43ED9C
- Molecule
- Aggrecan core protein
- UniProt
- P13608
- Pockets
- 17 · best druggability 0.75
Structure
1 distinct chain · 6% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aggrecan core protein | protein | 2364 | 6% helix, 19% strand | P13608 |
Pockets
17 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 986 | 0.75 | 0.78 | 82 | empty |
| 2 | 589 | 0.68 | 0.77 | 53 | empty |
| 3 | 114 | 0.67 | 0.90 | 22 | empty |
| 4 | 214 | 0.64 | 0.83 | 32 | empty |
| 5 | 167 | 0.63 | 0.84 | 33 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13608
- Elsewhere: UniProt P13608 · AlphaFold DB P13608
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