MolNFT v1 · #295830 · protein
AlphaFold monomer V2.0 prediction for formate acetyltransferase 1 (P09373)
P09373: “AlphaFold monomer V2.0 prediction for formate acetyltransferase 1 (P09373)”. 6 pockets (best druggability 0.68). MolNFT v1 #295830 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P09373
- Type
- protein
- Length
- 760 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- Formate acetyltransferase 1
- UniProt
- P09373
- Pockets
- 6 · best druggability 0.68
Structure
1 distinct chain · 48% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Formate acetyltransferase 1 | protein | 760 | 48% helix, 13% strand | P09373 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.68 | 0.88 | 35 | empty |
| 2 | 200 | 0.52 | 0.77 | 25 | empty |
| 3 | 69 | 0.39 | 0.79 | 20 | empty |
| 4 | 71 | 0.37 | 0.77 | 18 | empty |
| 5 | 56 | 0.35 | 0.79 | 15 | empty |
Compared structures
- 1CM5 · Crystal structure of C418A,C419A mutant of pfl from E.COLI · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1CM5 · Crystal structure of C418A,C419A mutant of pfl from E.COLI · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3PFL · Crystal structure of pfl from E.COLI in complex with substrate analogue oxamate · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3PFL · Crystal structure of pfl from E.COLI in complex with substrate analogue oxamate · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2PFL · Crystal structure of pfl from E.COLI · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2PFL · Crystal structure of pfl from E.COLI · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H18 · Pyruvate formate-lyase (E.COLI) in complex with pyruvate · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H18 · Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H16 · Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate and CoA · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H16 · Pyruvate formate-lyase (E.COLI) in complex with pyruvate and CoA · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H17 · Pyruvate formate-lyase (E.COLI) in complex with CoA and the substrate analog oxamate · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1H17 · Pyruvate Formate-Lyase (E.coli) in complex with CoA and the substrate analog oxamate · an experimental structure of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09373
- Elsewhere: UniProt P09373 · AlphaFold DB P09373
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