MolNFT v1 · #295411 · protein

AlphaFold monomer V2.0 prediction for vacuolar membrane protease (Q2GXG8)

Q2GXG8: “AlphaFold monomer V2.0 prediction for vacuolar membrane protease (Q2GXG8)”. 14 pockets (best druggability 0.80). MolNFT v1 #295411 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q2GXG8
Type: protein
Length: 995 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x54D4bc1Db8d05fA48ea46e4D5F03ad31Da5Ea445
Molecule: Vacuolar membrane protease
UniProt: Q2GXG8
Pockets: 14 · best druggability 0.80

Structure

1 distinct chain · 38% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vacuolar membrane protease	protein	995	38% helix, 17% strand	Q2GXG8

Pockets

14 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	327	0.80	0.90	50	empty
2	154	0.72	0.91	20	empty
3	131	0.67	0.89	24	empty
4	270	0.66	0.81	28	empty
5	412	0.63	0.78	54	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2GXG8
Elsewhere: UniProt Q2GXG8 · AlphaFold DB Q2GXG8

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