MolNFT v1 · #295160 · protein
AlphaFold monomer V2.0 prediction for prostaglandin F2-alpha receptor (P43088)
P43088: “AlphaFold monomer V2.0 prediction for prostaglandin F2-alpha receptor (P43088)”. 4 pockets (best druggability 0.83). MolNFT v1 #295160 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P43088
- Type
- protein
- Length
- 359 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
- Molecule
- Prostaglandin F2-alpha receptor
- UniProt
- P43088
- Pockets
- 4 · best druggability 0.83
Structure
1 distinct chain · 76% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prostaglandin F2-alpha receptor | protein | 359 | 76% helix, 1% strand | P43088 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 172 | 0.83 | 0.98 | 27 | empty |
| 2 | 406 | 0.67 | 0.79 | 43 | empty |
| 3 | 91 | 0.44 | 0.79 | 20 | empty |
| 4 | 172 | 0.43 | 0.74 | 24 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 8IUK · Cryo-EM structure of the PGF2-alpha-bound human PTGFR-Gq complex · an experimental structure of the same protein · chain A against R, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43088
- Elsewhere: UniProt P43088 · AlphaFold DB P43088
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