MolNFT v1 · #294187 · protein
AlphaFold monomer V2.0 prediction for thyroid peroxidase (P14650)
P14650: “AlphaFold monomer V2.0 prediction for thyroid peroxidase (P14650)”. 13 pockets (best druggability 0.83). MolNFT v1 #294187 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P14650
- Type
- protein
- Length
- 914 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
- Molecule
- Thyroid peroxidase
- UniProt
- P14650
- Pockets
- 13 · best druggability 0.83
Structure
1 distinct chain · 40% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thyroid peroxidase | protein | 914 | 40% helix, 13% strand | P14650 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 232 | 0.83 | 0.95 | 53 | empty |
| 2 | 964 | 0.81 | 0.83 | 93 | empty |
| 3 | 54 | 0.68 | 0.96 | 15 | empty |
| 4 | 382 | 0.67 | 0.80 | 36 | empty |
| 5 | 250 | 0.57 | 0.78 | 26 | empty |
Modifications
Observed in the structure: 13 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14650
- Elsewhere: UniProt P14650 · AlphaFold DB P14650
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