MolNFT v1 · #294120 · protein
AlphaFold monomer V2.0 prediction for eosinophil peroxidase (P11678)
P11678: “AlphaFold monomer V2.0 prediction for eosinophil peroxidase (P11678)”. 10 pockets (best druggability 0.81). MolNFT v1 #294120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P11678
- Type
- protein
- Length
- 715 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- Eosinophil peroxidase
- UniProt
- P11678
- Pockets
- 10 · best druggability 0.81
Structure
1 distinct chain · 41% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Eosinophil peroxidase | protein | 715 | 41% helix, 8% strand | P11678 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 160 | 0.81 | 0.97 | 31 | empty |
| 2 | 381 | 0.73 | 0.84 | 46 | empty |
| 3 | 273 | 0.65 | 0.82 | 28 | empty |
| 4 | 267 | 0.55 | 0.76 | 33 | empty |
| 5 | 75 | 0.51 | 0.85 | 20 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 8OGI · Structure of native human eosinophil peroxidase · an experimental structure of the same protein · chain A against B, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11678
- Elsewhere: UniProt P11678 · AlphaFold DB P11678
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