MolNFT v1 · #293559 · protein
AlphaFold monomer V2.0 prediction for periplakin (O60437)
O60437: “AlphaFold monomer V2.0 prediction for periplakin (O60437)”. 12 pockets (best druggability 0.54). MolNFT v1 #293559 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60437
- Type
- protein
- Length
- 1,756 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x507b0cF5c2F663afF8A05761eBf4e0Bf457a72Fb
- Molecule
- Periplakin
- UniProt
- O60437
- Pockets
- 12 · best druggability 0.54
Structure
1 distinct chain · 74% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Periplakin | protein | 1756 | 74% helix, 4% strand | O60437 |
Pockets
12 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 382 | 0.54 | 0.73 | 37 | empty |
| 2 | 298 | 0.53 | 0.75 | 24 | empty |
| 3 | 238 | 0.48 | 0.74 | 35 | empty |
| 4 | 148 | 0.44 | 0.75 | 20 | empty |
| 5 | 137 | 0.40 | 0.74 | 22 | empty |
Compared structures
- 4Q28 · Crystal structure of the plectin 1 and 2 repeats of the human periplakin. northeast… · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 4Q28 · Crystal Structure of the Plectin 1 and 2 Repeats of the Human Periplakin. Northeast… · an experimental structure of the same protein · chain A against A, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60437
- Elsewhere: UniProt O60437 · AlphaFold DB O60437
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