MolNFT v1 · #290727 · protein
AlphaFold monomer V2.0 prediction for high affinity camp-specific and ibmx-insensitive 3',5'-cyclic phosphodiesterase 8 (Q6NNF2)
Q6NNF2: “AlphaFold monomer V2.0 prediction for high affinity camp-specific and ibmx-insensitive 3',5'-cyclic…”. 10 pockets (best druggability 0.83). MolNFT v1 #290727 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6NNF2
- Type
- protein
- Length
- 914 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- High affinity camp-specific and ibmx-insensitive 3',5'-cyclic phosphodiesterase 8
- UniProt
- Q6NNF2
- Pockets
- 10 · best druggability 0.83
Structure
1 distinct chain · 41% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | High affinity camp-specific and ibmx-insensitive 3',5'-cyclic phosphodiesterase 8 | protein | 914 | 41% helix, 7% strand | Q6NNF2 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 284 | 0.83 | 0.94 | 48 | empty |
| 2 | 813 | 0.68 | 0.75 | 59 | empty |
| 3 | 80 | 0.64 | 0.91 | 20 | empty |
| 4 | 212 | 0.48 | 0.75 | 21 | empty |
| 5 | 141 | 0.45 | 0.76 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NNF2
- Elsewhere: UniProt Q6NNF2 · AlphaFold DB Q6NNF2
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