MolNFT v1 · #290605 · protein
AlphaFold monomer V2.0 prediction for dual 3',5'-cyclic-AMP and -gmp phosphodiesterase 11 (Q9VJ79)
Q9VJ79: “AlphaFold monomer V2.0 prediction for dual 3',5'-cyclic-AMP and -gmp phosphodiesterase 11 (Q9VJ79)”. 11 pockets (best druggability 0.81). MolNFT v1 #290605 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9VJ79
- Type
- protein
- Length
- 1,451 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x26ca9158879e824EF8a73775708d1b19082345Fc
- Molecule
- Dual 3',5'-cyclic-AMP and -gmp phosphodiesterase 11
- UniProt
- Q9VJ79
- Pockets
- 11 · best druggability 0.81
Structure
1 distinct chain · 36% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual 3',5'-cyclic-AMP and -gmp phosphodiesterase 11 | protein | 1451 | 36% helix, 7% strand | Q9VJ79 |
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 472 | 0.81 | 0.88 | 49 | empty |
| 2 | 181 | 0.63 | 0.84 | 24 | empty |
| 3 | 151 | 0.62 | 0.85 | 23 | empty |
| 4 | 473 | 0.59 | 0.74 | 47 | empty |
| 5 | 385 | 0.59 | 0.76 | 35 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9VJ79
- Elsewhere: UniProt Q9VJ79 · AlphaFold DB Q9VJ79
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