MolNFT v1 · #290512 · protein
AlphaFold monomer V2.0 prediction for PHOSPHOLIPID:DIACYLGLYCEROL acyltransferase (P40345)
P40345: “AlphaFold monomer V2.0 prediction for PHOSPHOLIPID:DIACYLGLYCEROL acyltransferase (P40345)”. 6 pockets (best druggability 0.80). MolNFT v1 #290512 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40345
- Type
- protein
- Length
- 661 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- PHOSPHOLIPID:DIACYLGLYCEROL acyltransferase
- UniProt
- P40345
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 36% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PHOSPHOLIPID:DIACYLGLYCEROL acyltransferase | protein | 661 | 36% helix, 12% strand | P40345 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.80 | 0.95 | 31 | empty |
| 2 | 999 | 0.72 | 0.76 | 66 | empty |
| 3 | 86 | 0.43 | 0.79 | 20 | empty |
| 4 | 51 | 0.34 | 0.78 | 14 | empty |
| 5 | 59 | 0.34 | 0.77 | 17 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40345
- Elsewhere: UniProt P40345 · AlphaFold DB P40345
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