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MolNFT v1 · #290396 · protein

AlphaFold monomer V2.0 prediction for choline-phosphate cytidylyltransferase a (P19836)

P19836: “AlphaFold monomer V2.0 prediction for choline-phosphate cytidylyltransferase a (P19836)”. 2 pockets (best druggability 0.74). MolNFT v1 #290396 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P19836
Type
protein
Length
367 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x1870f7A7de043458b061e1a3A5431D8b56e790fE
Molecule
Choline-phosphate cytidylyltransferase a
UniProt
P19836
Pockets
2 · best druggability 0.74

Structure

1 distinct chain · 38% helix, 8% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACholine-phosphate cytidylyltransferase aprotein36738% helix, 8% strandP19836

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12950.740.8637empty
2970.330.7322empty

Compared structures

  • 4MVD · Crystal structure of a mammalian cytidylyltransferase · an experimental structure of the same protein · chain A against B, TM-score 0.50
  • 4MVD · Crystal Structure of a Mammalian Cytidylyltransferase · an experimental structure of the same protein · chain A against B, TM-score 0.50
  • 4MVC · Crystal structure of a mammalian cytidylyltransferase · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 4MVC · Crystal Structure of a Mammalian Cytidylyltransferase · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 3HL4 · Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline · an experimental structure of the same protein · chain A against B, TM-score 0.47
  • 3HL4 · Crystal structure of a mammalian CTP:PHOSPHOCHOLINE cytidylyltransferase with cdp-choline · an experimental structure of the same protein · chain A against B, TM-score 0.47

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