MolNFT v1 · #290314 · protein
AlphaFold monomer V2.0 prediction for proprotein convertase SUBTILISIN/KEXIN type 6 (P29122)
P29122: “AlphaFold monomer V2.0 prediction for proprotein convertase SUBTILISIN/KEXIN type 6 (P29122)”. 8 pockets (best druggability 0.58). MolNFT v1 #290314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P29122
- Type
- protein
- Length
- 969 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Proprotein convertase SUBTILISIN/KEXIN type 6
- UniProt
- P29122
- Pockets
- 8 · best druggability 0.58
Structure
1 distinct chain · 14% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proprotein convertase SUBTILISIN/KEXIN type 6 | protein | 969 | 14% helix, 27% strand | P29122 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 310 | 0.58 | 0.77 | 36 | empty |
| 2 | 195 | 0.55 | 0.79 | 35 | empty |
| 3 | 219 | 0.54 | 0.78 | 35 | empty |
| 4 | 185 | 0.45 | 0.75 | 23 | empty |
| 5 | 115 | 0.44 | 0.78 | 35 | empty |
Modifications
Observed in the structure: 24 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29122
- Elsewhere: UniProt P29122 · AlphaFold DB P29122
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