GL1X · GenesisL1 explorer

MolNFT v1 · #289453 · protein

AlphaFold monomer V2.0 prediction for polycomb group ring finger protein 5 (Q86SE9)

Q86SE9: “AlphaFold monomer V2.0 prediction for polycomb group ring finger protein 5 (Q86SE9)”. 2 pockets (best druggability 0.58). MolNFT v1 #289453 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q86SE9
Type
protein
Length
256 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x0E31920A67aafd5e006BeA2a197680e7C7330186
Molecule
Polycomb group ring finger protein 5
UniProt
Q86SE9
Pockets
2 · best druggability 0.58

Structure

1 distinct chain · 25% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APolycomb group ring finger protein 5protein25625% helix, 17% strandQ86SE9

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13460.580.7640empty
2500.260.7415empty

Compared structures

  • 4S3O · PCGF5-RING1B-UBCH5C complex · an experimental structure of the same protein · chain A against C, TM-score 0.37
  • 4S3O · PCGF5-RING1B-UbcH5c complex · an experimental structure of the same protein · chain A against C, TM-score 0.37

Analyse

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