MolNFT v1 · #289068 · protein
AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (P31776)
P31776: “AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (P31776)”. 12 pockets (best druggability 0.72). MolNFT v1 #289068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P31776
- Type
- protein
- Length
- 853 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Penicillin-binding protein 1A
- UniProt
- P31776
- Pockets
- 12 · best druggability 0.72
Structure
1 distinct chain · 38% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 1A | protein | 853 | 38% helix, 16% strand | P31776 |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 810 | 0.72 | 0.77 | 75 | empty |
| 2 | 328 | 0.65 | 0.80 | 31 | empty |
| 3 | 226 | 0.57 | 0.79 | 26 | empty |
| 4 | 185 | 0.56 | 0.81 | 31 | empty |
| 5 | 145 | 0.44 | 0.76 | 24 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5U2G · 2.6 ångström resolution crystal structure of penicillin-binding protein 1A from… · an experimental structure of the same protein · chain A against B, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31776
- Elsewhere: UniProt P31776 · AlphaFold DB P31776
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