MolNFT v1 · #289021 · protein
AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchanger protein 7 (G5EBK1)
G5EBK1: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchanger protein 7 (G5EBK1)”. 12 pockets (best druggability 0.77). MolNFT v1 #289021 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- G5EBK1
- Type
- protein
- Length
- 783 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6F7e02049B13f0f0eF041D8589c607F441790c57
- Molecule
- NA(+)/H(+) exchanger protein 7
- UniProt
- G5EBK1
- Pockets
- 12 · best druggability 0.77
Structure
1 distinct chain · 72% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NA(+)/H(+) exchanger protein 7 | protein | 783 | 72% helix, 1% strand | G5EBK1 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1051 | 0.77 | 0.79 | 75 | empty |
| 2 | 583 | 0.72 | 0.80 | 71 | empty |
| 3 | 290 | 0.65 | 0.81 | 35 | empty |
| 4 | 374 | 0.60 | 0.77 | 35 | empty |
| 5 | 129 | 0.51 | 0.80 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G5EBK1
- Elsewhere: UniProt G5EBK1 · AlphaFold DB G5EBK1
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