GL1X · GenesisL1 explorer

MolNFT v1 · #288885 · protein

AlphaFold monomer V2.0 prediction for paxillin (Q8VI36)

Q8VI36: “AlphaFold monomer V2.0 prediction for paxillin (Q8VI36)”. 3 pockets (best druggability 0.49). MolNFT v1 #288885 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8VI36
Type
protein
Length
591 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
Molecule
Paxillin
UniProt
Q8VI36
Pockets
3 · best druggability 0.49

Structure

1 distinct chain · 19% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APaxillinprotein59119% helix, 13% strandQ8VI36

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12350.490.7436empty
2730.330.7513empty
3790.310.7416empty

Compared structures

  • 6JMU · Crystal structure of GIT1/Paxillin complex · an experimental structure of the same protein · chain A against C, TM-score 0.03
  • 6JMU · Crystal structure of GIT1/PAXILLIN complex · an experimental structure of the same protein · chain A against C, TM-score 0.03
  • 5W93 · p130Cas complex with paxillin LD1 · an experimental structure of the same protein · chain A against E, TM-score 0.02
  • 5W93 · P130CAS complex with paxillin LD1 · an experimental structure of the same protein · chain A against E, TM-score 0.02

Analyse

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