MolNFT v1 · #288729 · protein
AlphaFold monomer V2.0 prediction for poz-, at hook-, and zinc finger-containing protein 1 (Q9HBE1)
Q9HBE1: “AlphaFold monomer V2.0 prediction for poz-, at hook-, and zinc finger-containing protein 1 (Q9HBE1)”. 5 pockets (best druggability 0.61). MolNFT v1 #288729 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9HBE1
- Type
- protein
- Length
- 687 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x121FBE8cb498Fefb77e8499d91A1200302f3Fc6b
- Molecule
- Poz-, at hook-, and zinc finger-containing protein 1
- UniProt
- Q9HBE1
- Pockets
- 5 · best druggability 0.61
Structure
1 distinct chain · 27% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poz-, at hook-, and zinc finger-containing protein 1 | protein | 687 | 27% helix, 4% strand | Q9HBE1 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 553 | 0.61 | 0.74 | 54 | empty |
| 2 | 362 | 0.61 | 0.77 | 43 | empty |
| 3 | 90 | 0.32 | 0.72 | 16 | empty |
| 4 | 56 | 0.27 | 0.73 | 15 | empty |
| 5 | 51 | 0.25 | 0.73 | 11 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2YT9 · Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 2YT9 · Solution structure of C2H2 type zinc finger domain 345 in zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 2EPS · Solution structure of the 4TH zinc finger domain of zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPS · Solution structure of the 4th zinc finger domain of Zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPP · Solution structure of the first C2H2 type zinc finger domain of zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPP · Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPQ · Solution structure of the third zinc finger domain of Zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPQ · Solution structure of the third zinc finger domain of zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2EPR · Solution structure of the secound zinc finger domain of Zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2EPR · Solution structure of the secound zinc finger domain of zinc finger protein 278 · an experimental structure of the same protein · chain A against A, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HBE1
- Elsewhere: UniProt Q9HBE1 · AlphaFold DB Q9HBE1
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