MolNFT v1 · #288572 · protein
AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase (P35875)
P35875: “AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase (P35875)”. 10 pockets (best druggability 0.85). MolNFT v1 #288572 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P35875
- Type
- protein
- Length
- 994 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Poly [ADP-ribose] polymerase
- UniProt
- P35875
- Pockets
- 10 · best druggability 0.85
Structure
1 distinct chain · 34% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poly [ADP-ribose] polymerase | protein | 994 | 34% helix, 21% strand | P35875 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 922 | 0.85 | 0.86 | 122 | empty |
| 2 | 475 | 0.76 | 0.84 | 49 | empty |
| 3 | 824 | 0.72 | 0.77 | 55 | empty |
| 4 | 557 | 0.72 | 0.80 | 56 | empty |
| 5 | 224 | 0.54 | 0.77 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35875
- Elsewhere: UniProt P35875 · AlphaFold DB P35875
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