MolNFT v1 · #288553 · protein
AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2 (O50017)
O50017: “AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2 (O50017)”. 6 pockets (best druggability 0.79). MolNFT v1 #288553 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O50017
- Type
- protein
- Length
- 653 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Poly [ADP-ribose] polymerase 2
- UniProt
- O50017
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 34% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poly [ADP-ribose] polymerase 2 | protein | 653 | 34% helix, 21% strand | O50017 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 493 | 0.79 | 0.86 | 52 | empty |
| 2 | 910 | 0.79 | 0.81 | 89 | empty |
| 3 | 171 | 0.51 | 0.78 | 28 | empty |
| 4 | 76 | 0.40 | 0.78 | 17 | empty |
| 5 | 68 | 0.33 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O50017
- Elsewhere: UniProt O50017 · AlphaFold DB O50017
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