MolNFT v1 · #288496 · protein
AlphaFold monomer V2.0 prediction for POLY(ADP-ribose) glycohydrolase (O02776)
O02776: “AlphaFold monomer V2.0 prediction for POLY(ADP-ribose) glycohydrolase (O02776)”. 7 pockets (best druggability 0.74). MolNFT v1 #288496 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O02776
- Type
- protein
- Length
- 977 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- POLY(ADP-ribose) glycohydrolase
- UniProt
- O02776
- Pockets
- 7 · best druggability 0.74
Structure
1 distinct chain · 21% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(ADP-ribose) glycohydrolase | protein | 977 | 21% helix, 8% strand | O02776 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1188 | 0.74 | 0.77 | 104 | empty |
| 2 | 441 | 0.70 | 0.81 | 40 | empty |
| 3 | 476 | 0.66 | 0.78 | 47 | empty |
| 4 | 108 | 0.60 | 0.86 | 23 | empty |
| 5 | 101 | 0.39 | 0.75 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O02776
- Elsewhere: UniProt O02776 · AlphaFold DB O02776
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