MolNFT v1 · #288479 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit B (P0A2I6)
P0A2I6: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit B (P0A2I6)”. 6 pockets (best druggability 0.75). MolNFT v1 #288479 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0A2I6
- Type
- protein
- Length
- 630 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- DNA topoisomerase 4 subunit B
- UniProt
- P0A2I6
- Pockets
- 6 · best druggability 0.75
Structure
1 distinct chain · 38% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 4 subunit B | protein | 630 | 38% helix, 22% strand | P0A2I6 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 509 | 0.75 | 0.84 | 70 | empty |
| 2 | 195 | 0.46 | 0.74 | 25 | empty |
| 3 | 218 | 0.43 | 0.72 | 25 | empty |
| 4 | 159 | 0.43 | 0.75 | 22 | empty |
| 5 | 73 | 0.36 | 0.77 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A2I6
- Elsewhere: UniProt P0A2I6 · AlphaFold DB P0A2I6
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