MolNFT v1 · #288421 · protein
AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit a (Q6G9K4)
Q6G9K4: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit a (Q6G9K4)”. 6 pockets (best druggability 0.66). MolNFT v1 #288421 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6G9K4
- Type
- protein
- Length
- 800 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1bC4517e06e9f0cB40EF3CB193a013Ea75f77bf6
- Molecule
- DNA topoisomerase 4 subunit a
- UniProt
- Q6G9K4
- Pockets
- 6 · best druggability 0.66
Structure
1 distinct chain · 34% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 4 subunit a | protein | 800 | 34% helix, 25% strand | Q6G9K4 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 674 | 0.66 | 0.75 | 57 | empty |
| 2 | 212 | 0.48 | 0.75 | 30 | empty |
| 3 | 119 | 0.46 | 0.79 | 24 | empty |
| 4 | 171 | 0.46 | 0.76 | 26 | empty |
| 5 | 70 | 0.41 | 0.79 | 13 | empty |
Compared structures
- 2INR · Crystal structure of a 59 kDa fragment of topoisomerase IV subunit A (GrlA) from… · an experimental structure of the same protein · chain A against A, TM-score 0.54
- 2INR · Crystal structure of a 59 kda fragment of topoisomerase IV subunit a (grla) from… · an experimental structure of the same protein · chain A against A, TM-score 0.54
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6G9K4
- Elsewhere: UniProt Q6G9K4 · AlphaFold DB Q6G9K4
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