MolNFT v1 · #288245 · protein
AlphaFold monomer V2.0 prediction for POLY(A) polymerase alpha (P51003)
P51003: “AlphaFold monomer V2.0 prediction for POLY(A) polymerase alpha (P51003)”. 6 pockets (best druggability 0.74). MolNFT v1 #288245 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P51003
- Type
- protein
- Length
- 745 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- POLY(A) polymerase alpha
- UniProt
- P51003
- Pockets
- 6 · best druggability 0.74
Structure
1 distinct chain · 29% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(A) polymerase alpha | protein | 745 | 29% helix, 11% strand | P51003 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.74 | 0.96 | 26 | empty |
| 2 | 1093 | 0.74 | 0.77 | 82 | empty |
| 3 | 170 | 0.57 | 0.81 | 24 | empty |
| 4 | 127 | 0.45 | 0.77 | 16 | empty |
| 5 | 149 | 0.43 | 0.75 | 30 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51003
- Elsewhere: UniProt P51003 · AlphaFold DB P51003
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