MolNFT v1 · #286976 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q3AVB7)
Q3AVB7: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q3AVB7)”. 2 pockets (best druggability 0.68). MolNFT v1 #286976 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q3AVB7
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x41619aEaC82953337fdd56118cb265EE56Ce1F7E
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- Q3AVB7
- Pockets
- 2 · best druggability 0.68
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 270 | 44% helix, 14% strand | Q3AVB7 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.68 | 0.85 | 32 | empty |
| 2 | 217 | 0.55 | 0.78 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3AVB7
- Elsewhere: UniProt Q3AVB7 · AlphaFold DB Q3AVB7
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