GL1X · GenesisL1 explorer

MolNFT v1 · #286912 · protein

AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A3QHQ1)

A3QHQ1: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A3QHQ1)”. 2 pockets (best druggability 0.74). MolNFT v1 #286912 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
A3QHQ1
Type
protein
Length
264 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xAe60a245FF4c8aB8aEe81bfA8C2c2242098434D7
Molecule
3-methyl-2-oxobutanoate hydroxymethyltransferase
UniProt
A3QHQ1
Pockets
2 · best druggability 0.74

Structure

1 distinct chain · 45% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A3-methyl-2-oxobutanoate hydroxymethyltransferaseprotein26445% helix, 15% strandA3QHQ1

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12300.740.8835empty
2780.380.7721empty

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