MolNFT v1 · #286899 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B4TK05)
B4TK05: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B4TK05)”. 4 pockets (best druggability 0.66). MolNFT v1 #286899 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B4TK05
- Type
- protein
- Length
- 263 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- B4TK05
- Pockets
- 4 · best druggability 0.66
Structure
1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 263 | 46% helix, 14% strand | B4TK05 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 218 | 0.66 | 0.83 | 32 | empty |
| 2 | 99 | 0.44 | 0.78 | 14 | empty |
| 3 | 97 | 0.35 | 0.74 | 23 | empty |
| 4 | 57 | 0.27 | 0.73 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4TK05
- Elsewhere: UniProt B4TK05 · AlphaFold DB B4TK05
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