MolNFT v1 · #286860 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A4WMD4)
A4WMD4: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A4WMD4)”. 2 pockets (best druggability 0.72). MolNFT v1 #286860 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A4WMD4
- Type
- protein
- Length
- 264 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- A4WMD4
- Pockets
- 2 · best druggability 0.72
Structure
1 distinct chain · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 264 | 43% helix, 15% strand | A4WMD4 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 217 | 0.72 | 0.87 | 32 | empty |
| 2 | 85 | 0.41 | 0.78 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4WMD4
- Elsewhere: UniProt A4WMD4 · AlphaFold DB A4WMD4
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