MolNFT v1 · #286846 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A5W974)
A5W974: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A5W974)”. 3 pockets (best druggability 0.72). MolNFT v1 #286846 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A5W974
- Type
- protein
- Length
- 266 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF798f308FcD2a0138Cc80431D1879348A6451653
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- A5W974
- Pockets
- 3 · best druggability 0.72
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 266 | 44% helix, 14% strand | A5W974 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 318 | 0.72 | 0.84 | 36 | empty |
| 2 | 124 | 0.41 | 0.75 | 22 | empty |
| 3 | 75 | 0.33 | 0.75 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5W974
- Elsewhere: UniProt A5W974 · AlphaFold DB A5W974
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