MolNFT v1 · #286841 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q48N86)
Q48N86: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q48N86)”. 3 pockets (best druggability 0.71). MolNFT v1 #286841 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q48N86
- Type
- protein
- Length
- 266 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- Q48N86
- Pockets
- 3 · best druggability 0.71
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 266 | 44% helix, 14% strand | Q48N86 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 296 | 0.71 | 0.84 | 39 | empty |
| 2 | 109 | 0.39 | 0.75 | 21 | empty |
| 3 | 72 | 0.32 | 0.75 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q48N86
- Elsewhere: UniProt Q48N86 · AlphaFold DB Q48N86
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