MolNFT v1 · #286826 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B2RIF8)
B2RIF8: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B2RIF8)”. 3 pockets (best druggability 0.70). MolNFT v1 #286826 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B2RIF8
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0FAc74Bf23fFf003DE1B308Db5D5D92f90E0bFbd
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- B2RIF8
- Pockets
- 3 · best druggability 0.70
Structure
1 distinct chain · 43% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 273 | 43% helix, 14% strand | B2RIF8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.70 | 0.87 | 31 | empty |
| 2 | 111 | 0.43 | 0.77 | 22 | empty |
| 3 | 76 | 0.33 | 0.75 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2RIF8
- Elsewhere: UniProt B2RIF8 · AlphaFold DB B2RIF8
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