MolNFT v1 · #286774 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (P0C2T4)
P0C2T4: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (P0C2T4)”. 3 pockets (best druggability 0.66). MolNFT v1 #286774 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P0C2T4
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x904549575bEB2e311D9Afd0Ebf08d60F511A0c5A
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- P0C2T4
- Pockets
- 3 · best druggability 0.66
Structure
1 distinct chain · 42% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 281 | 42% helix, 14% strand | P0C2T4 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 239 | 0.66 | 0.83 | 34 | empty |
| 2 | 76 | 0.34 | 0.75 | 16 | empty |
| 3 | 70 | 0.30 | 0.73 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C2T4
- Elsewhere: UniProt P0C2T4 · AlphaFold DB P0C2T4
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