MolNFT v1 · #286708 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q74CG8)
Q74CG8: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q74CG8)”. 2 pockets (best druggability 0.71). MolNFT v1 #286708 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q74CG8
- Type
- protein
- Length
- 267 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- Q74CG8
- Pockets
- 2 · best druggability 0.71
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 267 | 44% helix, 14% strand | Q74CG8 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 308 | 0.71 | 0.84 | 39 | empty |
| 2 | 93 | 0.40 | 0.77 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q74CG8
- Elsewhere: UniProt Q74CG8 · AlphaFold DB Q74CG8
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