MolNFT v1 · #286671 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B7M175)
B7M175: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B7M175)”. 3 pockets (best druggability 0.66). MolNFT v1 #286671 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7M175
- Type
- protein
- Length
- 264 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd9e069D1339FAA95b9530BA8d5279541BF7Eeaab
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- B7M175
- Pockets
- 3 · best druggability 0.66
Structure
1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 264 | 46% helix, 14% strand | B7M175 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 239 | 0.66 | 0.83 | 32 | empty |
| 2 | 109 | 0.42 | 0.77 | 14 | empty |
| 3 | 114 | 0.40 | 0.75 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7M175
- Elsewhere: UniProt B7M175 · AlphaFold DB B7M175
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