MolNFT v1 · #286645 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B3R6G5)
B3R6G5: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (B3R6G5)”. 2 pockets (best druggability 0.73). MolNFT v1 #286645 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B3R6G5
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7A4EeC40C2bDEADd2390afB7c86D71Dc5673C0C4
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- B3R6G5
- Pockets
- 2 · best druggability 0.73
Structure
1 distinct chain · 42% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 273 | 42% helix, 15% strand | B3R6G5 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 244 | 0.73 | 0.87 | 37 | empty |
| 2 | 67 | 0.29 | 0.73 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B3R6G5
- Elsewhere: UniProt B3R6G5 · AlphaFold DB B3R6G5
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