MolNFT v1 · #286571 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q8K9U6)
Q8K9U6: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q8K9U6)”. 3 pockets (best druggability 0.70). MolNFT v1 #286571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8K9U6
- Type
- protein
- Length
- 263 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x41CeC9196Eb401e6912C97187dA1a9626eD4e80D
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- Q8K9U6
- Pockets
- 3 · best druggability 0.70
Structure
1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 263 | 44% helix, 14% strand | Q8K9U6 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 260 | 0.70 | 0.85 | 39 | empty |
| 2 | 93 | 0.41 | 0.77 | 20 | empty |
| 3 | 58 | 0.30 | 0.75 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8K9U6
- Elsewhere: UniProt Q8K9U6 · AlphaFold DB Q8K9U6
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