MolNFT v1 · #286563 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q57F29)
Q57F29: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (Q57F29)”. 2 pockets (best druggability 0.72). MolNFT v1 #286563 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q57F29
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e6CB3F4bbF31275436e823feE87C31AAE72E3cA
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- Q57F29
- Pockets
- 2 · best druggability 0.72
Structure
1 distinct chain · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 275 | 43% helix, 15% strand | Q57F29 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 220 | 0.72 | 0.87 | 33 | empty |
| 2 | 57 | 0.36 | 0.78 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57F29
- Elsewhere: UniProt Q57F29 · AlphaFold DB Q57F29
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