MolNFT v1 · #286531 · protein
AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A0RBZ2)
A0RBZ2: “AlphaFold monomer V2.0 prediction for 3-methyl-2-oxobutanoate hydroxymethyltransferase (A0RBZ2)”. 3 pockets (best druggability 0.65). MolNFT v1 #286531 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0RBZ2
- Type
- protein
- Length
- 279 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x260D6D743e9CB293CAd7D5d61915104457dde2eD
- Molecule
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- UniProt
- A0RBZ2
- Pockets
- 3 · best druggability 0.65
Structure
1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-methyl-2-oxobutanoate hydroxymethyltransferase | protein | 279 | 46% helix, 14% strand | A0RBZ2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 208 | 0.65 | 0.83 | 29 | empty |
| 2 | 121 | 0.41 | 0.75 | 19 | empty |
| 3 | 98 | 0.35 | 0.74 | 25 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0RBZ2
- Elsewhere: UniProt A0RBZ2 · AlphaFold DB A0RBZ2
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