MolNFT v1 · #286112 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 2 (Q13177)

Q13177: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 2 (Q13177)”. 4 pockets (best druggability 0.77). MolNFT v1 #286112 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q13177
Type: protein
Length: 524 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf97f120f1cAC0985138AF468D0d17B7b3f67FB36
Molecule: SERINE/THREONINE-protein kinase pak 2
UniProt: Q13177
Pockets: 4 · best druggability 0.77

Structure

1 distinct chain · 33% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase pak 2	protein	524	33% helix, 12% strand	Q13177

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1007	0.77	0.79	76	empty
2	121	0.50	0.80	26	empty
3	115	0.37	0.74	20	empty
4	58	0.26	0.73	20	empty

Compared structures

3PCS · Structure of espg-PAK2 autoinhibitory IALPHA3 helix complex · an experimental structure of the same protein · chain A against H, TM-score 0.02
3PCS · Structure of EspG-PAK2 autoinhibitory Ialpha3 helix complex · an experimental structure of the same protein · chain A against H, TM-score 0.02

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13177
Elsewhere: UniProt Q13177 · AlphaFold DB Q13177

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