GL1X · GenesisL1 explorer

MolNFT v1 · #285056 · protein

AlphaFold monomer V2.0 prediction for acidic phospholipase A2 2 (P60044)

P60044: “AlphaFold monomer V2.0 prediction for acidic phospholipase A2 2 (P60044)”. 1 pocket (best druggability 0.62). MolNFT v1 #285056 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P60044
Type
protein
Length
126 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule
Acidic phospholipase A2 2
UniProt
P60044
Pockets
1 · best druggability 0.62

Structure

1 distinct chain · 49% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAcidic phospholipase A2 2protein12649% helix, 9% strandP60044

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12330.620.8224empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

  • 1S6B · X-ray crystal structure of a complex formed between two homologous isoforms of… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 1S6B · X-ray Crystal Structure of a Complex Formed Between Two Homologous Isoforms of… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 2RD4 · Design of specific inhibitors of phospholipase A2: crystal structure of the complex of… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 2RD4 · Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 1XXW · Structure of zinc induced heterodimer of two calcium free isoforms of phospholipase A2… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 1XXW · Structure of zinc induced heterodimer of two calcium free isoforms of phospholipase A2… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 1MH2 · Crystal structure of a zinc containing dimer of phospholipase A2 from the venom of indian… · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 1MH2 · Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian… · an experimental structure of the same protein · chain A against B, TM-score 0.92

Analyse

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