MolNFT v1 · #284661 · protein

AlphaFold monomer V2.0 prediction for prolyl 4-hydroxylase 2 (F4JAU3)

F4JAU3: “AlphaFold monomer V2.0 prediction for prolyl 4-hydroxylase 2 (F4JAU3)”. 5 pockets (best druggability 0.66). MolNFT v1 #284661 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: F4JAU3
Type: protein
Length: 299 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x94AA95F893B4A9504df68b74731983419e54EBc3
Molecule: Prolyl 4-hydroxylase 2
UniProt: F4JAU3
Pockets: 5 · best druggability 0.66

Structure

1 distinct chain · 27% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Prolyl 4-hydroxylase 2	protein	299	27% helix, 26% strand	F4JAU3

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.66	0.82	44	empty
2	325	0.58	0.77	35	empty
3	57	0.38	0.80	12	empty
4	62	0.32	0.76	14	empty
5	56	0.28	0.74	16	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F4JAU3
Elsewhere: UniProt F4JAU3 · AlphaFold DB F4JAU3

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