MolNFT v1 · #284474 · protein
AlphaFold monomer V2.0 prediction for protein phosphatase 2C 77 (O04719)
O04719: “AlphaFold monomer V2.0 prediction for protein phosphatase 2C 77 (O04719)”. 3 pockets (best druggability 0.63). MolNFT v1 #284474 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O04719
- Type
- protein
- Length
- 423 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- Protein phosphatase 2C 77
- UniProt
- O04719
- Pockets
- 3 · best druggability 0.63
Structure
1 distinct chain · 30% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein phosphatase 2C 77 | protein | 423 | 30% helix, 18% strand | O04719 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 333 | 0.63 | 0.79 | 38 | empty |
| 2 | 103 | 0.48 | 0.80 | 22 | empty |
| 3 | 50 | 0.39 | 0.81 | 14 | empty |
Compared structures
- 3UJK · Crystal structure of protein phosphatase ABI2 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 3UJK · Crystal structure of protein phosphatase ABI2 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 3NMV · Crystal structure of pyrabactin-bound abscisic acid receptor PYL2 mutant A93F in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.65
- 3NMV · Crystal structure of pyrabactin-bound abscisic acid receptor PYL2 mutant A93F in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.65
- 3UJL · Crystal structure of abscisic acid bound PYL2 in complex with type 2C protein phosphatase… · an experimental structure of the same protein · chain A against B, TM-score 0.64
- 3UJL · Crystal structure of abscisic acid bound PYL2 in complex with type 2C protein phosphatase… · an experimental structure of the same protein · chain A against B, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O04719
- Elsewhere: UniProt O04719 · AlphaFold DB O04719
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