MolNFT v1 · #283998 · protein
AlphaFold monomer V2.0 prediction for orexin receptor type 2 (P56719)
P56719: “AlphaFold monomer V2.0 prediction for orexin receptor type 2 (P56719)”. 7 pockets (best druggability 0.81). MolNFT v1 #283998 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P56719
- Type
- protein
- Length
- 460 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4199EeC82b849fde39B880b988Ac2427d713765e
- Molecule
- Orexin receptor type 2
- UniProt
- P56719
- Pockets
- 7 · best druggability 0.81
Structure
1 distinct chain · 62% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Orexin receptor type 2 | protein | 460 | 62% helix, 2% strand | P56719 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 639 | 0.81 | 0.86 | 47 | empty |
| 2 | 495 | 0.68 | 0.78 | 40 | empty |
| 3 | 171 | 0.50 | 0.77 | 23 | empty |
| 4 | 100 | 0.46 | 0.80 | 17 | empty |
| 5 | 65 | 0.35 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56719
- Elsewhere: UniProt P56719 · AlphaFold DB P56719
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